Symptom Management SeriesHyperactive Terminal Delirium in Hospice Patients A Retrospective Cohort StudyKates, Jeannette PhD, APRN, AGPCNP-BC, GNP-BC Author Information Jeannette Kates, PhD, APRN, AGPCNP-BC, GNP-BC, is assistant professor and director Adult-Gerontology Primary Care Nurse Practitioner Program, Thomas Jefferson University College of Nursing, Philadelphia, PA. Address correspondence to Jeannette Kates, PhD, APRN, AGPCNP-BC, GNP-BC, Thomas Jefferson University College of Nursing, 130 S Ninth St, Philadelphia, PA 19107 ([email protected]). The author has no conflicts of interest to disclose. This study was supported by the Thomas Jefferson University College of Nursing Seed Money Grant. Journal of Hospice & Palliative Nursing: April 2020 - Volume 22 - Issue 2 - p 95-100 doi: 10.1097/NJH.0000000000000631 Buy CE Test Metrics Abstract Terminal delirium is a common occurrence in patients at the end of life, and its presence is widely accepted as a poor prognostic indicator. The hyperactive subtype is characterized by psychomotor agitation that is distressing to patients, caregivers, and providers. The purpose of this study was to determine whether physical, psychosocial, or spiritual data collected at hospice admission are associated with development of hyperactive terminal delirium. In this retrospective cohort study, 154 patients were assigned to one of two cohorts depending on whether or not they had signs of hyperactive terminal delirium. Hospice admission data from the Hospice Item Set, psychosocial assessment, and spiritual assessment were analyzed using descriptive statistics, inferential statistics, and logistic regression. Although there were no statistically significant relationships among the physical, psychosocial, and spiritual variables and hyperactive terminal delirium, there were some findings that are clinically significant for nurses caring for patients at the end of life. Specifically, this study highlights the importance of ongoing physical, psychosocial, and spiritual assessment throughout the end-of-life trajectory, as well as prompt management of symptoms. Copyright © 2020 by The Hospice and Palliative Nurses Association. All rights reserved.