DEPARTMENTS: Drugs in DermatologyUse of 5-Fluorouracil “Chemowraps” as a Method of Field Therapy for Actinic Keratosis and Adjunctive Therapy for Squamous Cell CarcinomaHeath, Christopher; Zito, Patrick M.Author Information Christopher Heath, MS, Lake Erie College of Osteopathic Medicine, Erie, PA. Patrick M. Zito, DO, PharmD, RPh, FASCP, FRSPH, College of Health Sciences, School of Nursing, Walden University, Minneapolis, MN. The authors declare no conflict of interest. Correspondence concerning this article should be addressed to Patrick M. Zito, DO, PharmD, RPh, FASCP, FRSPH, College of Health Sciences, School of Nursing, Walden University, 100 Washington Ave., S. Suite 900, Minneapolis, MN 55401. E-mail: Patrick.firstname.lastname@example.org Journal of the Dermatology Nurses’ Association: November/December 2019 - Volume 11 - Issue 6 - p 292-294 doi: 10.1097/JDN.0000000000000504 Buy Metrics Abstract ABSTRACT Drugs are medications or substances that are used to modify physiologic responses and alleviate associated symptoms. In dermatology, medications and substances are utilized on a daily basis and include topical treatments to anesthetics in micrographic surgery to biologic-acting immunologic agents. The purposes of this section are to focus on drug, specifically how it works and how it is utilized, and to discuss routine alternatives (if available). In this column, we will focus on the uses, mechanism of action, adverse effects, and alternatives of 5-fluorouracil used in chemowraps for actinic keratoses and squamous cell carcinoma. Copyright © 2019 by the Dermatology Nurses' Association.