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Pentoxifylline (Trental) in Venous Insufficiency and Venous Leg Ulcers

Zito, Patrick M.; Murgia, Robert D. III

Journal of the Dermatology Nurses' Association: November/December 2018 - Volume 10 - Issue 6 - p 294–296
doi: 10.1097/JDN.0000000000000437
DEPARTMENTS: Drugs in Dermatology

ABSTRACT Drugs are medications or substances that are used to modify physiologic responses and alleviate associated symptoms. In dermatology, medications and substances are utilized on a daily basis and include topical treatments to anesthetics in micrographic surgery to biologic-acting immunologic agents. The purposes of this section are to focus on drug, specifically how it works and how it is utilized, and to discuss routine alternatives (if available). In this column, we will focus on the uses, mechanism of action, adverse effects, and alternatives to pentoxifylline (Trental, Pentoxil) in venous leg ulcers.

Patrick M. Zito, DO, PharmD, RPh, FASCP, FRSPH, College of Health Sciences, School of Nursing, Walden University, Minneapolis, MN.

Robert D. Murgia III, DO, Department of Dermatology, Hackensack-Meridian Health, Palisades, NJ.

The authors declare no conflict of interest.

Correspondence concerning this article should be addressed to Patrick M. Zito, DO, PharmD, RPh, FASCP, FRSPH, College of Health Sciences, School of Nursing, Walden University, 100 Washington Ave., S. Suite 900, Minneapolis, MN 55401. E-mail: Patrick.zito@waldenu.edu

Copyright © 2018 by the Dermatology Nurses' Association.