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Daylight-Mediated Photodynamic Therapy for Actinic Keratosis: Best Practice Guidelines

Spelman, Lynda; Holland, Teagan; Davidson, Kurt

Journal of the Dermatology Nurses' Association: July/August 2018 - Volume 10 - Issue 4 - p 201–204
doi: 10.1097/JDN.0000000000000421

ABSTRACT Actinic (solar) keratoses are premalignant lesions caused by prolonged exposure to ultraviolet radiation, with the potential to progress into squamous cell carcinoma. Hence, use of appropriate therapies is critical for effective treatment. Daylight-mediated photodynamic therapy with methyl aminolevulinate cream is a convenient new option for the safe and effective treatment of actinic (solar) keratosis lesions, offering similar efficacy to conventional photodynamic therapy, nearly painless treatment, and reduced in-clinic times. Use of appropriate therapies and optimization of clinical practice are critical for safe and effective treatment. Nurses play a key role in ensuring best clinical practice and effective treatment. This article explains the practicalities and principles of daylight-mediated photodynamic therapy to ensure best practice by treating nurses.

Lynda Spelman, MBBS, Specialist Connect Pty Ltd, Woolloongabba, Queensland, Australia; Veracity Clinical Research Pty Ltd, Woolloongabba, Queensland, Australia.

Teagan Holland, RN,Veracity Clinical Research Pty Ltd, Woolloongabba, Queensland, Australia.

Kurt Davidson, BASc, Veracity Clinical Research Pty Ltd, Woolloongabba, Queensland, Australia.

The authors declare no conflict of interest.

Correspondence concerning this article should be addressed to Spelman Lynda, MBBS, Specialist Connect Pty. Ltd., 68 Ipswich Road, Woolloongabba, QLD 4102, Australia. E-mail:

Reprinted with permission from Journal of the Dermatology Nurse’s Association, 8(4):265-268, July/August 2016.

Copyright © 2018 by the Dermatology Nurses' Association.