Two-surgeon, two-center evaluation of a new combined EDOF intraocular lens approach : Journal of Cataract & Refractive Surgery

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Two-surgeon, two-center evaluation of a new combined EDOF intraocular lens approach

Mastropasqua, Leonardo MD; Pedrotti, Emilio MD, PhD; Ruggeri, Maria Ludovica MD; Vecchiarino, Luca MD; Bonacci, Erika MD; Guarini, Daniele MD; Falconio, Gennaro MD; Toto, Lisa MD, PhD; Marchini, Giorgio MD, PhD

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Journal of Cataract & Refractive Surgery 49(5):p 512-517, May 2023. | DOI: 10.1097/j.jcrs.0000000000001145


To evaluate visual performance and quality of life after bilateral implantation of 2 extended depth-of-focus intraocular lenses (EDOF IOLs).


Ophthalmology Clinic, Department of Medicine and Science of Ageing, University “G. d'Annunzio” Chieti-Pescara, Italy, and Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy.


Prospective clinical study.


60 eyes of 30 patients with senile cataract were enrolled in this study. Patients underwent phacoemulsification and bilateral implantation of the Mini WELL IOL in the dominant eye and the Mini WELL PROXA IOL in the nondominant eye within a month. The main outcome measures over a 3-month follow-up period were uncorrected and corrected visual acuity at different distances (33 cm, 60 cm, and 4 m), defocus curve, contrast sensitivity, and patient satisfaction (evaluated by mean of the National Eye Institute Refractive Error Quality-of-Life instrument-42 questionnaire).


Binocular uncorrected visual acuity at 90 days was 0.03 ± 0.11 logMAR for long distance, 0.05 ± 0.10 logMAR for intermediate distance, 0.03 ± 0.08 logMAR at 40 cm, and 0.06 ± 0.08 logMAR at 33 cm. Statistically significant differences between the 2 EDOF IOLs in favor of Mini WELL PROXA IOL were observed for uncorrected near visual acuity at 40 and 33 cm (P < .001 and P < .001, respectively) and for distance-corrected near visual acuity at 40 cm (P < .001). Significant differences between the 2 IOLs in the defocus curves were reported.


In this small pilot study, bilateral implantation of Mini WELL IOL and Mini WELL PROXA IOL achieved good quantity and quality of vision.

Copyright © 2023 Published by Wolters Kluwer on behalf of ASCRS and ESCRS

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