ArticleFemtosecond laser–assisted cataract surgery in Fuchs endothelial corneal dystrophy: Long-term outcomesFan, Wei MD; Yan, Hua MD, PhD*; Zhang, Guangbin MD Author Information From the Department of Ophthalmology (Fan, Yan), Tianjin Medical University General Hospital, Tianjin, and the Department of Cataract (Fan, Zhang), Xiamen Ophthalmic Center, Affiliate Xiamen University, Xiamen, China *Corresponding author: Hua Yan, MD, PhD, Department of Ophthalmology, Tianjin Medical University General Hospital, Number 154 Anshan Road, Tianjin 300052, China. E-mail: [email protected] Submitted February 8, 2018; revised April 8, 2018; accepted May 4, 2018. Supported by the National Natural Science Foundation of China (No. 81670865) and Tianjin Science and Technology Support Program (13ZCZDSY02400).Figure: No Caption available.First author: Wei Fan, MD Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China Journal of Cataract & Refractive Surgery: July 2018 - Volume 44 - Issue 7 - p 864-870 doi: 10.1016/j.jcrs.2018.05.007 Buy Metrics Abstract Purpose To compare the corneal endothelial cell loss and central corneal thickness (CCT) after conventional phacoemulsification surgery or femtosecond laser–assisted cataract surgery in patients with Fuchs endothelial corneal dystrophy and senile cataract. Setting Xiamen Ophthalmic Center, Affiliate Xiamen University, Xiamen, China. Design Prospective case series. Methods Eyes with mild or moderate Fuchs endothelial corneal dystrophy and cataracts had femtosecond laser–assisted cataract surgery or phacoemulsification. The endothelial cell density (ECD), rate of ECD loss, cumulative dissipated energy (CDE), and CCT were measured preoperatively and 3 days and 1, 3, 6, and 12 months postoperatively. Results The study evaluated 31 eyes. The CDE was lower in the femtosecond group than in the phacoemulsification group (P < .05). The preoperative and postoperative ECDs were similar in the 2 groups (P > .05). The rate of ECD loss was higher in the phacoemulsification group from 1 to 12 months postoperatively (P > .05). The CCT was thicker in the phacoemulsification group 1, 3, and 6 months postoperatively (all P > .05). In both groups, the postoperative CCT at all follow-up visits were greater than the preoperative CCT (all P < .01). No bullous keratopathy or other intraoperative complications occurred in either group during the follow-up. Conclusions For eyes with Fuchs endothelial corneal dystrophy and cataract, the CCT 12 months after surgery remained thicker than the preoperative thickness. The femtosecond group, with a lower CDE, tended to have a thinner CCT and less endothelial cell loss than the phacoemulsification group. © 2018 by Lippincott Williams & Wilkins, Inc.
