ArticleAspheric versus wavefront-guided aspheric photorefractive keratectomy in eyes with significant astigmatismFaramarzi, Amir MD*; Moshirfar, Majid MD; Karimian, Farid MD; Delfazayebaher, Siamak MD; Kheiri, Bahareh MS Author Information From the Ophthalmic Research Center and Department of Ophthalmology (Faramarzi, Karimian, Delfazayebaher, Kheiri), Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; John A Moran Eye Center (Moshirfar), Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA *Corresponding author: Amir Faramarzi, MD, Ophthalmic Research Center, Ophthalmology Department, Labbafinejad Medical Center, Pasdaran Avenue, Boostan 9 Street, Tehran 1666694516, Iran. E-mail: [email protected] Submitted May 16, 2017; revised August 29, 2017; accepted September 4, 2017.Figure: No Caption available.First author: Amir Faramarzi, MD Ophthalmic Research Center, Ophthalmology Department, Labbafinejad Medical Center, Tehran, Iran Journal of Cataract & Refractive Surgery: December 2017 - Volume 43 - Issue 12 - p 1534-1540 doi: 10.1016/j.jcrs.2017.09.022 Buy Metrics Abstract Purpose To compare the refractive and higher-order aberrations (HOAs) outcomes after photorefractive keratectomy (PRK) in patients with significant astigmatism using aspheric versus wavefront-guided aspheric profiles. Setting Ophthalmic Research Center and Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Negah Eye Hospital, Tehran, Iran. Design Prospective randomized case series. Methods One eye of each patient with a refractive astigmatism more than 2.00 diopters (D) randomly received aspheric PRK. In the other eye, wavefront-guided and aspheric treatment was performed using a personalized treatment advanced algorithm. Visual acuity, refractive errors, and HOAs were compared between the 2 groups preoperatively and 12 months postoperatively. Results The study comprised 32 patients (64 eyes). The mean preoperative refractive astigmatism was −4.07 D ± 1.64 (SD) and −4.02 ± 1.55 D in the aspheric group and wavefront-guided aspheric group, respectively (P = .2). The mean postoperative astigmatism was −0.46 ± 0.37 D and −0.82 ± 0.53 D in the aspheric group and wavefront-guided aspheric group, respectively (P = .02). Postoperatively, the root mean square of total HOAs was significantly increased in both groups. However, compared with wavefront-guided aspheric PRK, aspheric PRK induced fewer HOAs (P = .003). Conclusions In eyes with high astigmatism, post-PRK residual astigmatism was lower in the aspheric group than in the wavefront-guided aspheric group. The increase in HOAs was significantly higher in the wavefront-guided aspheric group than in the aspheric group. © 2017 by Lippincott Williams & Wilkins, Inc.
