Articles: PDF OnlyOcufen and pupillary dilation during cataract surgeryDrews, Robert C. M.D.1, a; Katsev, Douglas A. M.D.2, 3Author Information 1From the Department of Ophthalmology, Washington University, St. Louis, Missouri 2Department of Ophthalmology, St. Louis University, St. Louis, Missouri 3Bethesda Eye Institute aReprint requests to Robert C. Drews, M.D., 211 North Meramee Avenue, Clayton, Missouri 63105. Journal of Cataract & Refractive Surgery: July 1989 - Volume 15 - Issue 4 - p 445-448 doi: 10.1016/S0886-3350(89)80068-9 Buy Metrics Abstract A random, masked prospective study was performed on 100 patients having elective extracapsular cataract extraction to evaluate the ability of Ocufen® (flurbiprofen) to maintain dilation of the pupil. All the patients received a standard dilating regimen; half also received Ocufen drops. Surgery was recorded with a video camera attached to the operating microscope. Magnification was kept constant. Pupil diameters were measured on a calibrated video screen at four different stages of the operation: at the beginning, post-capsulotomy, post-nucleus delivery, and at the end. The age, sex, and iris color of each patient were recorded. Preoperative pupillary diameters were not statistically different between the control and Ocufen groups. The Ocufen-treated group maintained pupillary dilation better on the average and had a much smaller incidence of pupil constriction greater than 2 mm. © Williams & Wilkins 1989. All Rights Reserved.