Brief and Case ReportsCardio-Oncology Rehabilitation (CORE) Exercise Prescription and Programming A PRACTICAL GUIDEShultz, Adam M. MS; Squires, Ray W. PhD; Shin, John Y. MD; Durani, Urshila MD; Pophali, Priyanka A. MDAuthor Information Department of Cardiovascular Medicine, Division of Preventive Cardiology, Mayo Clinic, Rochester, Minnesota (Mr Shultz and Dr Squires); Department of Hematology/Oncology, Mayo Clinic, Rochester, Minnesota (Drs Shin and Durani); and Division of Hematology, Oncology and Palliative Care, University of Wisconsin, Madison (Dr Pophali). Correspondence: Adam M. Shultz, MS, Department of Cardiovascular Medicine, Division of Preventive Cardiology, Mayo Clinic, 200 First St Southwest, Rochester, MN 55905 ([email protected]). The authors declare no conflicts of interest. Supplemental digital content is available for this article. Direct URL citation appears in the printed text and is provided in the HTML and PDF versions of this article on the journal's Web site (www.jcrpjournal.com). Journal of Cardiopulmonary Rehabilitation and Prevention: September 2021 - Volume 41 - Issue 5 - p 341-344 doi: 10.1097/HCR.0000000000000572 Buy SDC Metrics AbstractIn Brief Background: Patients with cancer almost universally report diminished health-related quality of life. Many patients experience persistent fatigue and most have below-average exercise capacities. Despite the publication of exercise guidelines for cancer survivors that encourage physical activity, few patients exercise on a regular basis. Cardiovascular disease is a major cause of death in early-stage malignancies. Exercise training has been demonstrated to decrease cardiovascular events in patients with cancer. In addition, regular exercise improves exercise capacity, reduces fatigue, and improves quality of life in cancer survivors. Clinical Considerations: A 2019 American Heart Association scientific statement, endorsed by the American Cancer Society, provided a framework and rationale for partnering with existing multidimensional, interdisciplinary outpatient cardiac rehabilitation programs to provide supervised exercise training and risk factor control services for patients with cancer and cancer survivors: cardio-oncology rehabilitation. In addition, the American College of Sports Medicine has published recommendations for cancer exercise training. Summary: This article provides practical suggestions for incorporating patients with cancer into cardiac rehabilitation and for patient-specific exercise prescription. Illustrative patient case examples are provided. Cardio-oncology rehabilitation (CORE) is the utilization of existing multidimensional outpatient cardiac rehabilitation programs to provide supervised exercise training for cancer survivors at risk for cardiovascular disease. This article describes our experience with CORE and provides practical suggestions for incorporating cancer survivors into cardiac rehabilitation. We also discuss patient-specific exercise prescription suggestions and provide illustrative case examples. © 2021 Wolters Kluwer Health, Inc. All rights reserved.