In persons with and without cardiovascular disease, an elevated resting heart rate, systolic blood pressure, or both, may serve as independent and additive predictors of acute cardiovascular events and increased mortality. Several pathophysiologic mechanisms may explain these relationships. Accordingly, these “vital signs” may be more intricately linked with survival than previously perceived.
Preventive Cardiology and Cardiac Rehabilitation, Department of Cardiovascular Medicine, Beaumont Health, Royal Oak, Michigan (Drs Franklin and Chaddha); and Internal Medicine, Oakland University William Beaumont School of Medicine, Rochester, Michigan (Dr Franklin).
Correspondence: Barry A. Franklin, PhD, MAACVPR, FACSM, FAHA, Preventive Cardiology and Cardiac Rehabilitation, Department of Cardiovascular Medicine, Beaumont Health and Wellness Center, 4949 Coolidge Hwy, Royal Oak, MI 48073 (Barry.Franklin@Beaumont.edu).
The authors declare no conflicts of interest.