Influence of Smartphone Wi-Fi Signals on Adipose-Derived Stem Cells : Journal of Craniofacial Surgery

Secondary Logo

Journal Logo

Scientific Foundation

Influence of Smartphone Wi-Fi Signals on Adipose-Derived Stem Cells

Lee, Sang-Soon MD, PhD*; Kim, Hyung-Rok MD*; Kim, Min-Sook MS*; Park, Sanghoon PhD; Yoon, Eul-Sik MD, PhD*; Park, Seung-Ha MD, PhD*; Kim, Deok-Woo MD, PhD*

Author Information
The Journal of Craniofacial Surgery 25(5):p 1902-1907, September 2014. | DOI: 10.1097/SCS.0000000000000939


The use of smartphones is expanding rapidly around the world, thus raising the concern of possible harmful effects of radiofrequency generated by smartphones. We hypothesized that Wi-Fi signals from smartphones may have harmful influence on adipose-derived stem cells (ASCs). An in vitro study was performed to assess the influence of Wi-Fi signals from smartphones. The ASCs were incubated under a smartphone connected to a Wi-Fi network, which was uploading files at a speed of 4.8 Mbps for 10 hours a day, for a total of 5 days. We constructed 2 kinds of control cells, one grown in 37°C and the other grown in 39°C. After 5 days of Wi-Fi exposure from the smartphone, the cells underwent cell proliferation assay, apoptosis assay, and flow cytometry analysis. Three growth factors, vascular endothelial growth factor, hepatocyte growth factor, and transforming growth factor-β, were measured from ASC-conditioned media. Cell proliferation rate was higher in Wi-Fi–exposed cells and 39°C control cells compared with 37°C control cells. Apoptosis assay, flow cytometry analysis, and growth factor concentrations showed no remarkable differences among the 3 groups. We could not find any harmful effects of Wi-Fi electromagnetic signals from smartphones. The increased proliferation of ASCs under the smartphone, however, might be attributable to the thermal effect.

© 2014 by Mutaz B. Habal, MD.

You can read the full text of this article if you:

Access through Ovid