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The Treatment Strategy of Cleidocranial Dysplasia

Combined Orthodontic and Orthognathic Treatment

Li, Juan DDS*; Shen, Jiawei DDS*; Xu, Ji DDS; Weng, Luxi DDS*; Pan, Jiale MM; Lin, Jun DDS, PhD*

doi: 10.1097/SCS.0000000000005372
Clinical Study: PDF Only

Cleidocranial dysplasia is a rare autosomal-dominant condition that affects ossification. The main symptoms of this cleidocranial dysplasia patient include craniofacial abnormalities, hypoplasia of clavicles, narrow thorax, retarded exfoliation of deciduous teeth, retarded eruption of permanent teeth, and multiple impacted supernumerary teeth. The aim of this treatment was to correct the craniofacial abnormalities and provide an adequate functional reconstruction of the occlusion. The patient was treated with a multidisciplinary therapeutic protocol including removal of supernumerary teeth, surgical exposure of impacted teeth, orthodontic, and orthognathic surgery. After 6 years’ follow-up, the treatment objectives of acceptable occlusion, normal function, and acceptable profile were achieved.

*Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University

Stomotology Hospital Affiliated to Zhejiang University of Medicine

Zhejiang Chinese Medical University, Hangzhou, China.

Address correspondence and reprint requests to Jun Lin, DDS, PhD, Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qin Chun Road 79, Hangzhou, Zhejiang Province, China; E-mail:,

Received 4 December, 2018

Accepted 5 January, 2019

JL and JS are cofirst authors.

This work was supported by Zhejiang Provincial Natural Science Foundation of China (Grant No.: LQ18H140004) and Zhejiang Provincial Medical & Hygienic Science and Technology Project of China (Grant No.: 2018256920).

The authors report no conflicts of interest.

© 2019 by Mutaz B. Habal, MD.