Brief Clinical Studies: PDF OnlySaliva as a Potential Diagnostic Specimen for COVID-19 TestingHarikrishnan, Pandurangan FDSRCS(Eng), PhDAuthor Information Craniofacial Orthodontics and Oral Surgery, Teeth “N” Jaws Center, Chennai, India. Address correspondence and reprint requests to Dr Pandurangan Harikrishnan, FDSRCS(Eng), PhD, Craniofacial Orthodontist and Oral Surgeon, Teeth ”N” Jaws Center, 23 & 25, Lake Area 1st Cross Street, Nungambakkam, Chennai, 600034, Tamil Nadu, India; E-mail: email@example.com Received 30 April, 2020 Accepted 6 May, 2020 The authors have no conflicts of interest to disclose. Journal of Craniofacial Surgery: June 11, 2020 - Volume Publish Ahead of Print - Issue - doi: 10.1097/SCS.0000000000006724 Free PAP Metrics Abstract The current outbreak of the highly contagious, animal origin SARS-CoV-2 virus causes the disease COVID-19. The disease is globally pandemic and as per World Health Organization (WHO) has spread to 235 countries. There is global lockdown for containment of the virus transmission. Testing of symptomatic patients, healthcare workers and suspected individuals and mass screening is vital. WHO recommends nasopharyngeal (NP) and oropharyngeal (OP) swab for the quantitative assessment of SARS-CoV-2 RNA level through real-time reverse transcription polymerase chain reaction (rRT-PCR). The virus is shown to be consistently present in saliva and rRTPCR of saliva specimens and have advantages over NP and OP swabs such as self-collection of saliva, avoidance of healthcare workers for specimen collection, cost-effectiveness, etc. This article explores the current literature and suggests saliva as an emerging potential diagnostic specimen for COVID-19 testing. © 2020 by Mutaz B. Habal, MD.