Brief Clinical StudiesMetastatic Prostate Adenocarcinoma of the Mandible Diagnosed With Oral ManifestationsAyranci, Ferhat DDS, PhD; Omezli, Mehmet Melih DDS, PhD; Torul, Damla DDS, PhD; Ay, Mustafa DDSAuthor Information Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ordu University, Ordu, Turkey. Address correspondence and reprint requests to Mustafa Ay, DDS, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ordu University, Ordu, Turkey; E-mail: email@example.com Received 10 July, 2019 Accepted 19 August, 2019 The authors report no conflicts of interest. Journal of Craniofacial Surgery: May 2020 - Volume 31 - Issue 3 - p e220-e222 doi: 10.1097/SCS.0000000000006025 Buy Metrics Abstract Metastasis from the prostate gland to the mandible is rarely encountered and commonly present with non-specific features like unexplained pain, swelling, and numb chin syndrome. Here we present a case with metastatic prostate adenocarcinoma detected secondary to oral manifestations. Patients present with unexplained facial pain and numbness should alert clinicians to the presence of malignant disease, and appropriate hematological, radiological and or histological investigations should be performed. Thereby, clinicians can prevent the overlook of the first signs of metastasis, accelerate the early diagnosis and positively orientate the prognosis of the disease, especially in a patient without known malignancy. © 2020 by Mutaz B. Habal, MD.