Original ArticlesComputational Evaluation of Potential Correction Methods for Unicoronal CraniosynostosisBozkurt, Selim PhD*,†; Borghi, Alessandro PhD†,‡; Jeelani, Owase FRCS(NeuroSurg)†,‡; Dunaway, David FRCS(Plast)†,‡; Schievano, Silvia PhD*,†Author Information *University College London, Institute of Cardiovascular Science, Department of Children's Cardiovascular Disease †University College London, Institute of Child Health, Department of Developmental Biology and Cancer ‡Great Ormond Street Hospital for Children, London, UK. Address correspondence and reprint requests to Selim Bozkurt, PhD, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK; E-mail: email@example.com Received 5 May, 2019 Accepted 19 October, 2019 This research was supported by the Great Ormond Street Hospital Children's Charity through the FaceValue program grant (no. 508857), the Engineering and Physical Sciences Research Council award (EP/N02124X/1), and the European Research Council Starting Grant (CAD4FACE/757923). This work was undertaken at GOSH/ICH, UCLH/UCL who received a proportion of funding from the United Kingdom Department of Health's NIHR Biomedical Research Center funding scheme. The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). Journal of Craniofacial Surgery: May 2020 - Volume 31 - Issue 3 - p 692-696 doi: 10.1097/SCS.0000000000006186 Buy SDC Metrics Abstract Unicoronal craniosynostosis is the second most common type of nonsyndromic craniosynostosis: it is characterized by ipsilateral forehead and fronto-parietal region flattening with contralateral compensatory bossing. It is a complex condition; therefore, which is difficult to treat because of the asymmetry in the orbits, cranium, and face. The aim of this study is to understand optimal osteotomy locations, dimensions, and force requirements for surgical operations of unicoronal craniosynostosis using a patient-specific finite element model and — at the same time — to evaluate the potential application of a new device made from Nitinol which was developed to expand the affected side of a unicoronal craniosynostosis skull without performing osteotomies. The model geometry was reconstructed using Simpleware ScanIP. The bone and sutures were modeled using elastic properties to perform the finite element analyses in MSc Marc software. The simulation results showed that expanding the cranium without osteotomy requires a significant amount of force. Therefore, expansion of the cranium achieved by Nitinol devices may not be sufficient to correct the deformity. Moreover, the size and locations of the osteotomies are crucial for an optimal outcome from surgical operations in unicoronal craniosynostosis. © 2020 by Mutaz B. Habal, MD.