Brief Clinical StudiesStafne Bone Defect Involving the Ascending RamusLee, Kevin C. DDS, MD*; Yoon, Angela J. DDS, MPH†; Philipone, Elizabeth M. DMD†; Peters, Scott M. DDS†Author Information *Department of Oral and Maxillofacial Surgery †Division of Oral and Maxillofacial Pathology, Columbia University College of Dental Medicine, New York, NY. Address correspondence and reprint requests to Scott M. Peters, DDS, Assistant Professor, Division of Oral and Maxillofacial Pathology, Columbia University Medical Center, 630 West 168th Street PH15-1562W, New York, NY 10032; E-mail: Smp2140@columbia.edu Received 1 September, 2018 Accepted 14 November, 2018 The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcraniofacialsurgery.com). Journal of Craniofacial Surgery: June 2019 - Volume 30 - Issue 4 - p e301-e303 doi: 10.1097/SCS.0000000000005252 Buy SDC Metrics Abstract The Stafne bone defect (SBD) classically presents as a well-defined, radiolucent lesion in the molar-mandibular angle region beneath the level of the mandibular canal. Due in large part to this prototypical appearance, most cases of SBDs are radiographically diagnostic without the need for tissue biopsy. A diagnostic challenge may arise, however, when the SBD occurs in other locations in the mandible. The authors report a case of a 57-year-old male who presented with a SBD of the left ascending ramus. The lesion was found incidentally on a panoramic radiograph. Additional imaging studies confirmed a lingual concavity of the mandibular bone consistent with a SBD, and a retrospective study of the patient's records revealed the presence of the lesion 5 years prior without any radiographic alterations. To date, only 10 documented cases of an SBD involving the ascending ramus have been reported. The rarity of such a presentation may obscure the diagnosis and lead to unwarranted surgical procedures. It is important to recognize atypically located SBDs, because unlike other radiolucent lesions, imaging studies are diagnostic. With proper diagnosis, additional surgical procedures and any associated morbidities can be avoided. © 2019 by Mutaz B. Habal, MD.