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Clinical and Radiological Comparison of Effects of Platelet-Rich Plasma, Hyaluronic Acid, and Corticosteroid Injections on Temporomandibular Joint Osteoarthritis

Gokçe Kutuk, Sinem MD*; Gökçe, Gökçen MD; Arslan, Muhammet MD; Özkan, Yasemin MD§; Kütük, Mustafa MD||; Kursat Arikan, Osman MD

Journal of Craniofacial Surgery: June 2019 - Volume 30 - Issue 4 - p 1144–1148
doi: 10.1097/SCS.0000000000005211
Clinical Studies
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There are few studies in the literature that comparatively evaluate the use of intra-articular orticosteroids (CS), hyaluronic acid (HA), and platelet-rich plasma (PRP). In this study, the authors aimed to compare the clinical results of intra-articular CS, HA, and PRP injections in patients who presented to the authors’ clinic with temporomandibular joint (TMJ) pain and clinically diagnosed with TMJ-osteoarthritis. Patients were evaluated in 2 groups as those patients who felt pain on lateral (n = 31), and posterior (n = 43) palpation. Patients who were evaluated in the study were randomly assigned to 3 different treatment groups as Group 1 (PRP), Group 2 (HA), and Group 3 (CS). Pain felt on the TMJ on lateral and posterior palpation was assessed before treatment and every month for 3 months using a 5-point pain scale. Presence of crepitation, loss of function, and loss of strength were assessed before treatment and every month for 3 months. Significant changes were observed in the PRP and HA groups when the patients were evaluated according to the VAS scores evaluated at different follow-up times for TMJ pain on lateral palpation. Significant changes were observed in the PRP, HA, and CS groups when VAS scores were evaluated according to the patients’ follow-up times for TMJ pain on lateral palpation. In conclusion, the findings of this study have shown that intra-articular PRP injections decreased TMJ palpation pain more effectively compared with the HA and CS groups.

*Department of Otorhinolaryngology, Aydin State Hospital, Aydin

Department Histology and Embryology, Faculty of Medicine, Afyon Kocatepe University, Afyon

Department of Radiology, Faculty of Medicine, Pamukkale University, Denizli

§Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Adnan Menderes University

||Department of Anesthesia and Rehabilitation, Aydin State Hospital, Aydin

Department of Otorhinolaryngology, Adana Numune Training and Research Hospital, Saglik Bilimleri University, Adana, Turkey.

Address correspondence and reprint requests to Sinem Gokçe Kutuk, MD, Department of Otorhinolaryngology, Aydin State Hospital, Aydin 09100, Turkey; E-mail: drsinem2@gmail.com

Received 9 August, 2018

Accepted 31 October, 2018

The authors report no conflicts of interest.

© 2019 by Mutaz B. Habal, MD.