Secondary Logo

Institutional members access full text with Ovid®

Three-Dimensional Stereophotogrammetric Evaluation of the Efficacy of Autologous Fat Grafting in the Treatment of Parry-Romberg Syndrome

Pucciarelli, Valentina, MBiotech, PhD*; Baserga, Camilla, MD†,‡; Codari, Marina, MSBE, PhD§; Beltramini, Giada A., MD†,‡; Sforza, Chiarella, MD, PhD*; Giannì, Aldo Bruno, MD†,‡

doi: 10.1097/SCS.0000000000004664
Clinical Studies

Autologous fat grafting is a surgical procedure used to correct volumetric defects, atrophies, and sclerosis. Three-dimensional (3D) facial photography may enable researchers to quantify the success of surgical procedures through volumetric and surface assessments. Using 3D photography, the authors assessed the results of autologous fat grafting performed in a 15-year-old patient affected by Parry-Romberg syndrome, a rare condition resulting in progressive hemifacial atrophy of skin, subcutaneous tissues and, ultimately, bone. Stereophotogrammetric acquisitions were performed before and 4 months after the surgical intervention. The obtained results were objectively assessed in terms of facial symmetry through calculation of root mean square deviation point-to-point distance between the treated and healthy side, and volume modifications between pre- and postsurgical 3D facial scans. Four months after surgery, 73% of injected adipose tissue was resorbed, whereas facial symmetry increased up to 63%. The proposed method is not invasive and provides quantitative information about the surgical and esthetic outcomes. Clinicians could better plan surgery, and the patients could be more motivated and compliant to the treatment.

*Laboratory of Functional Anatomy of the Stomatognathic System, Department of Biomedical Sciences for Health, Università degli Studi di Milano

Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano

Maxillofacial and Dental Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano

§Unit of Radiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.

Address correspondence and reprint requests to Chiarella Sforza, MD, PhD, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy; E-mail:

Received 19 December, 2017

Accepted 12 April, 2018

Drs CS and ABG contributed equally to this paper.

The authors report no conflicts of interest.

© 2018 by Mutaz B. Habal, MD.