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Clinical Efficacy and Patient Perceptions of Pyogenic Granuloma Excision Using Diode Laser Versus Conventional Surgical Techniques

Isola, Gaetano, DDS, PhD*,†; Matarese, Giovanni, DDS*; Cervino, Gabriele, DDS, PhD*; Matarese, Marco, DDS*; Ramaglia, Luca, DDS, PhD; Cicciù, Marco, DDS, PhD*

doi: 10.1097/SCS.0000000000004734
Clinical Studies

The use of laser in oral surgery and periodontology is a matter of debate, mainly because of the lack of consensual therapeutic protocols. The aim of this study was to evaluate the surgical advantages of diode laser versus traditional surgery with a cold blade for the surgical excision of pyogenic granuloma (PG). Twenty-one patients (10 males, 11 females, aged 19–66 years; mean age: 46.5 years), requiring PG excision, were enrolled in the study. Through a randomized clinical trial design, all patients were randomly subjected to PG surgical excision with either diode laser or cold blade. Parameters analyzed were the speed of incision, time of intervention, intraoperative bleeding, number of stitches, and patient compliance. Histologic examination was performed before and after surgical excision of the lesions. Patients compiled a subjective evaluation questionnaire. Both treatments were successful in surgical excision of PG. However, the mean speed of incision was significantly reduced in diode laser group (0.61 ± 0.29 mm/s) compared with cold blade group (1.47 ± 1.23 mm/s) (P < 0.05). The mean lengths of time for the whole surgical intervention were significantly lower in diode laser group (221.15 ± 220.89 s) compared with cold blade group (316.10 ± 248.69 s) (P < 0.05). Moreover, diode laser induced a reduced intrasurgical bleeding, and a better gingival healing compared with cold blade surgical treatment. This study demonstrated that the use of diode laser showed additional advantages compared with cold blade in terms of less postoperative discomfort and pain for surgical removal of PG.

*Department of Biomedical, Odontostomatological, Sciences and Morphological and Functional Images, School of Dentistry, University of Messina, Messina

Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.

Address correspondence and reprint requests to Marco Cicciù, DDS, PhD, Associate Professor of Biomedical, Dental Sciences and Morphology and Functional Images, Dental School, University of Messina, G. Martino Polyclinic, Via Consolare Valeria, 98100 Messina, Italy; E-mail:

Received 2 March, 2018

Accepted 15 May, 2018

The authors report no conflicts of interest.

© 2018 by Mutaz B. Habal, MD.