Brief Clinical StudiesIsolated Bilateral MacrostomiaPradhan, Rohan MS; Lin, Bojie PhD; Pan, Xin-Yuan PhD; Yin, Guo-Qian PhDAuthor Information Department of Plastic and Aesthetic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China. Address correspondence and reprint requests to Guo-Qian Yin, PhD, Department of Plastic and Aesthetic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, People's Republic of China; E-mail: email@example.com Received 8 December, 2017 Accepted 16 March, 2018 The authors report no conflicts of interest. Journal of Craniofacial Surgery: September 2018 - Volume 29 - Issue 6 - p e588-e590 doi: 10.1097/SCS.0000000000004621 Buy Metrics Abstract Macrostomia (Tessier's 7 cleft) is a rare congenital lip deformity. Macrostomia can occur unilateral or bilateral, isolated or associated with other syndromes. Isolated bilateral macrostomia is exceedingly rare with only a few cases reported to date. The authors report 6 cases of isolated bilateral macrostomia surgically repaired in 4-layered approaches. The traditional method was improved and the result obtained was satisfactory after longest follow-up of 3 years. The technique is easy to imitate, simple in design, aesthetically and functionally corrects the deformity. © 2018 by Mutaz B. Habal, MD.