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Sinonasal Leiomyoma With Estrogen Receptor Expression

Kim, Jong Seung MD*; Shin, Jin Yong MD; Kwon, Sam Hyun MD, PhD

doi: 10.1097/SCS.0000000000002011
Brief Clinical Studies

Leiomyoma is an extremely rare tumor in sinonasal area. The reason for this is due to minimal amount of the smooth muscle in the area. The origin of this tumor is not clear and its etiology has not been proven in the literature. A 58-year-old woman who experienced nasal obstruction and epiphora visited our clinic. A huge mass was noted in right nasal cavity originating from the lacrimal bone area. The authors conducted endoscopic sinus surgery and obtained the specimen. Immunochemistry showed leiomyoma in the nasal cavity, which expressed estrogen receptor. There was no progesterone receptor expressed. The authors describe a sinonasal leiomyoma with estrogen receptors, not ever reported in previous article.

*Department of Otolaryngology-Head and Neck Surgery

Department of Plastic and Reconstructive Surgery, Chonbuk National University

Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea.

Address correspondence and reprint requests to Sam Hyun Kwon, MD,PhD, 2-20 Keum-Am-Dong, Department of Otolaryngology-Head and Neck Surgery, Chonbuk National University Medical School, Jeonju 561-180, Republic of Korea; E-mail:

Received 9 May, 2015

Accepted 27 May, 2015

The authors report no conflicts of interest.

© 2015 by Mutaz B. Habal, MD.