Primary dural lymphoma (PDL), a rare subtype of primary central nervous system lymphoma (PCNSL), is usually a marginal zone B-cell lymphoma or low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type. Primary dural invasion by diffuse large B-cell lymphoma is extremely rare, with only a few cases reported in the literature. The authors presented an unusual case of primary dural involvement by a high-grade diffuse large B-cell lymphoma that invaded parietal bone and subcutaneous tissue. The patient received tumor complete resection and cranioplasty as well as radiotherapy and chemotherapy as adjuvant treatment after surgery. During 12 months follow-up, no tumor recurrence was found. Primary dural lymphoma should be differentially diagnosed with meningioma. Once the diagnosis of PDL is established, tumor resection and adjuvant radiation and chemotherapy may obtain relatively good prognosis.
*Department of Neurosurgery, Affiliated Heping Hospital of Chang Zhi Medical College, Chang Zhi, Shanxi
†Department of Neurosurgery
‡Department of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan
§Department of Endocrinology and Metabolism, Affiliated Heping Hospital of Chang Zhi Medical College, Chang Zhi, Shanxi, China.
Address correspondence and reprint requests to Fang Wang, MD, PhD, Department of Endocrinology and Metabolism, Affiliated Heping Hospital of Chang Zhi Medical College, Chang Zhi, Shanxi, China; E-mail: firstname.lastname@example.org
Received 9 April, 2015
Accepted 22 May, 2015
The authors report no conflict of interest.