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New and Successful Technique for the Management of Parry-Romberg Syndrome's Soft Tissue Atrophy

Ortega, Viviana Gómez MD*; Sastoque, Daniel MD

doi: 10.1097/SCS.0000000000002023
Brief Clinical Studies

Parry-Romberg syndrome (PRS) is an infrequent, acquired disorder characterized by progressive hemiatrophy of the skin and soft tissue of the face and, in some patients, results in atrophy of muscles, cartilage, and the underlying bony structures.

The disease process exhibits varying speeds of development, with onset occurring in early infancy or adolescence. Clinicians have classically reserved treatment until the end of the process. Various treatment modalities have been attempted with differing results. Described treatments include free tissue transfer (omentum, rectus, latissimus, serratus, diep, scapula, and parascapular), pedicled flaps, autologous tissue (dermis-fat, bone and cartilage, and fat), and biomaterials (silicone, polyethylene, and Alloderm).

In this article, the authors present a patient of Parry-Romberg syndrome in a young boy who had undergone a free flap previously, which failed to fill the atrophy of the right hemifacial soft tissues. The authors used Integra, which is a bilayer porous matrix of cross-linked bovine tendon collagen and glycosaminoglycan, and a semipermeable polysiloxane (silicone layer) and fat grafts enriched with Harvest PRP, to produce volume and symmetric contour on the affected side. The patient had a follow up of 2 years with excellent esthetic and functional results.

Objective: The authors present a technique of volume replacement in patients with hemifacial atrophy because of Parry-Romberg syndrome, which has never been reported before in the international literature.

Study: Microsurgical reconstruction is considered the gold standard to restore facial symmetry. Given a free flap morbidity and risk of complications, some patients opt for less extensive procedures. The authors present the case of a 12-year-old boy with a history of Parry-Romberg syndrome with resultant right hemifacial atrophy. Consistent with the usual pattern of atrophy, the onset of the patient's disease began at the age of 5 years.

Methods: The senior authors used a combination of a stacked Integra cheek implant and fat grafts enriched with Harvest PRP to produce volume and symmetric contour on the affected side. The patient was discharged home the next day after the surgical procedure from the recovery room, without complications.

Results: The patient was followed for 2 years. He has had no complications and maintains an excellent symmetric result. The patient is highly satisfied with his result and has not required any further surgery. Preoperative and postoperative photos at year of follow up are presented.

Discussion: Less invasive treatment options exist for hemifacial atrophy from Parry-Romberg syndrome.

*Plastic and Reconstructive Surgery Department of the Hospital Simón Bolivar and La Fundación Santa Fé de Bogotá and Hospital de la Policia

Plastic and Reconstructive Surgery Department of the Hospital Simón Bolivar, Bogota, Columbia.

Address correspondence and reprint requests to Viviana Gómez Ortega, MD, Hospital Simón Bolivar, Fundación Santa Fé de Bogotá, Hospital de la Policia, Cra 7ª. No 121-33, Bogotá, Colombia; E-mail:

Received 15 January, 2015

Accepted 28 June, 2015

The authors report no conflicts of interests.

© 2015 by Mutaz B. Habal, MD.