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Early Fat Grafting for Augmentation of Orbitozygomatic Region in Treacher Collins Syndrome

Konofaos, Petros MD, PhD*,†; Arnaud, Eric MD

Journal of Craniofacial Surgery: June 2015 - Volume 26 - Issue 4 - p 1258–1260
doi: 10.1097/SCS.0000000000001722
Clinical Studies

This report presents our preliminary experience with the effect of early fat grafting (FG) (at ≥6 months of age) in timely bone reconstruction of the orbitozygomatic area in patients with Treacher Collins syndrome. FG is performed 2 to 3 consecutive times after the age 6 months. Bone reconstruction is performed ≥6 months after the last FG session. This protocol was applied in 3 patients. There was no need for further reconstruction of the lower eyelids in 2 patients. Malar bone reconstructions, using calvarial bone grafts, were performed in all of the patients. Eighteen months after bone reconstruction, there was limited absorption of the bone grafts. Early FG of the orbitozygomatic area improves contour and tissue quality, restores volume, and can possibly minimize bone resorption following zygomatic bone framework reconstruction.

*Department of Plastic Surgery, University of Tennessee, Memphis, TN

Craniofacial Unit, Department of Pediatric Neurosurgery, Necker Hospital, Paris, France.

Address correspondence and reprint requests to Dr Eric Arnaud, MD, Craniofacial Unit, Department of Pediatric Neurosurgery, Necker Hospital, 34 Ave d’ Eylau, Paris 75116, France; E-mail:

Received 27 March, 2014

Accepted 1 November, 2014

The authors report no conflicts of interest.

© 2015 by Mutaz B. Habal, MD.