Brief Clinical StudiesEpistaxis and Staphylococcus aureus Colonization in the Nasal Vestibule: Is It a Cause or Consequence?Ulusoy, Seckin MD*; Babaoglu, Gulcin MD†; Catli, Tolgahan MD‡; San, Turhan MD§; Cingi, Cemal MD∥Author Information From the Departments of *Otorhinolaryngology, †Clinical Microbiology, Çorlu State Hospital, Tekirdag; ‡Department of Otorhinolaryngology, Bozyaka Teaching and Research Hospital, Izmir; §Department of Otorhinolaryngology, Istanbul Medeniyet University, Istanbul; and ∥Department of Otorhinolaryngology, Eskişehir Osmangazi University, Medical Faculty, Eskişehir, Turkey. Received November 11, 2013. Accepted for publication April 7, 2014. Address correspondence and reprint requests to Tolgahan Catli, MD, Department of Otorhinolaryngology, Bozyaka Teaching and Research Hospital, Izmir, Turkey; E-mail: firstname.lastname@example.org The authors report no conflicts of interest. The Journal of Craniofacial Surgery: November 2014 - Volume 25 - Issue 6 - p e513-e515 doi: 10.1097/SCS.0000000000001015 Buy Metrics Abstract The aim of this study was to investigate the relation between epistaxis and nasal colonization of Staphylococcus aureus in a population of patients with recurrent epistaxis. A total of 361 men and women were recruited, 245 patients with epistaxis (114 had crusting in the nasal vestibule; 131 did not) and 116 control subjects. A microbiology swab was taken from the anterior nasal cavity of each subject. Staphylococcus aureus was found to be more common in the epistaxis group when compared with the control group with a percentage of 31.8% and 4.3%, respectively (P < 0.05). There was no difference in the prevalence of S. aureus between the crust and non–crust groups (P > 0.05). When positive cultures were grouped and compared according to season, it was observed that the positive culture with epistaxis was much higher (44.82 %) in the autumn period. Staphylococcus aureus colonization in the nasal vestibule is more likely to be observed in individuals who have recurrent epistaxis than in those who do not have. It seems that this colonization may have a role in the etiology of epistaxis. However, with an altered medium of the nasal vestibule after each epistaxis period, it is also possible to speculate that this colonization is may be the consequence of epistaxis itself. © 2014 by Mutaz B. Habal, MD.