Long-term anthropometric follow-up of cranial vault growth may considerably add valuable information to current literature focusing on treatment strategies for premature multiple-suture craniosynostosis. The aim of this paper was to compare postoperative growth patterns of nonsyndromic and syndromic multiple-suture craniosynostotic children with sex-matched and age-matched children from the typically developing population. Forty-one multiple-suture craniosynostotic patients (19 nonsyndromic and 22 syndromic) were included in this 5-year follow-up. Anthropological data of sex-matched and age-matched normal Swiss children served as a control. A standardized time protocol for anthropometric skull measurements (head circumference and cephalic index) was used. Data were converted into Z-scores for standardized intercenter comparison. All patients showed a marked benefit in cranial vault shape after open skull remodeling. Significant differences in long-term cranial vault growth pattern could be seen between the nonsyndromic and the syndromic groups compared to the control group.
From the Department of Cranio-Maxillofacial and Oral Surgery, University of Zurich, Zurich, Switzerland.
Received August 28, 2012.
Accepted for publication December 13, 2013.
Address correspondence and reprint requests to Philipp Metzler, MD, DMD, Department of Cranio-Maxillofacial and Oral Surgery, University of Zurich, Frauenklinikstrasse 24, 8091 Zurich, Switzerland; E-mail: Philipp.Metzler@usz.ch
The authors report no conflicts of interest.