We aimed to obtain nationally representative data on hospital readmission rates after Guillain–Barre syndrome (GBS).
International Classification of Disease, Ninth Revision codes from the 2013 National Readmissions Database identified adult GBS admissions, comorbidities, and readmission diagnoses. Logistic regression estimated odds ratios (ORs) for readmission.
Of 2109 GBS admissions identified, 20.8% were readmitted within 1 year and 12.2% within 30 days. Age did not predict readmission. Plasmapheresis use showed a nonsignificant trend toward readmission versus intravenous immunoglobulin use [OR 1.43, 95% confidence interval (CI) 1.00–2.051, P = 0.050]. Respiratory failure (OR 1.70, 95% CI 1.23–2.35, P = 0.0014), heart failure (OR 2.14, 95% CI 1.25–3.66, P = 0.0057), and renal failure (OR 2.00, 95% CI 1.20–3.32, P = 0.0078) predicted readmission. Top readmission diagnoses included GBS or chronic inflammatory demyelinating polyneuropathy (42.0%) and sepsis (3.5%).
One-fifth of GBS patients were readmitted within 1 year. Comorbid illnesses and respiratory complications increased a readmission risk but age did not.