Review ArticleOutcome Measures in Myasthenia Gravis: Incorporation Into Clinical PracticeMuppidi, Srikanth MDAuthor Information Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA. Reprints: Srikanth Muppidi, MD, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305 (e-mail: email@example.com). Supported by Alexion Pharmaceuticals, Inc (New Haven, CT). Editorial and writing assistance has been provided to the author by Connexion Healthcare (Newtown, PA). The author meets the criteria for authorship as recommended by the International Committee of Medical Journal Editors (ICMJE), and is fully responsible for all content. S. Muppidi has served on scientific advisory boards for Alexion Pharmaceuticals, Inc and Lundbeck. Journal of Clinical Neuromuscular Disease: March 2017 - Volume 18 - Issue 3 - p 135-146 doi: 10.1097/CND.0000000000000156 Buy Metrics Abstract The development of validated assessment tools for evaluating disease status and response to interventions in patients with myasthenia gravis (MG) has been driven by clinical studies of emerging MG therapies. However, only a small proportion of MG-focused neurology practices have adopted these assessment tools for routine clinical use. This article reviews the suitability of 5 assessment instruments for incorporation into clinical practice, which should be driven by their ability to contribute to improved patient outcomes, and to be implemented within practice personnel and resource constraints. It is recommended that assessments based on both physician-evaluated and patient-reported outcomes be selected, to adequately evaluate both point-in-time symptom load and functional impact of MG symptoms over time. Provider resource allocation and reimbursement issues may be the most significant roadblocks to successful ongoing use of these tools; to that end, the addition of regular assessments to MG standards of care is recommended. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.