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Posterior Reversible Encephalopathy Syndrome Resulting From Guillain-Barré-Like Syndrome Secondary to West Nile Virus Infection

Abraham, Alon MD*; Ziv, Sari MD; Drory, Vivian E MD*‡

Journal of Clinical Neuromuscular Disease: March 2011 - Volume 12 - Issue 3 - p 113-117
doi: 10.1097/CND.0b013e318209ef9a
Case Review
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A 67-year-old woman developed hypertension, drowsiness, hemianopia, ascending flaccid tetraparesis, and areflexia. Nerve conduction studies revealed a demyelinating polyneuropathy. Brain magnetic resonance imaging demonstrated hyperintense white matter lesions. IgM antibodies against West Nile virus were positive. She was treated for hypertension and with intravenous immunoglobulins and recovered completely within 2 months. To our knowledge, this is the first case in which West Nile virus infection presented as posterior reversible encephalopathy syndrome associated with Guillain-Barré-like syndrome.

From the Departments of *Neurology and †Internal Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel; and ‡Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Reprints: Alon Abraham, MD, Department of Neurology, Tel-Aviv Sourasky Medical Center, 6 Weizmann Street, Tel-Aviv 64239, Israel (e-mail: alonabmail@gmail.com).

© 2011 Lippincott Williams & Wilkins, Inc.