Alternative Medicines for Cardiovascular DiseasesCoenzyme Q10 and Cardiovascular Disease: A ReviewSarter, Barbara PhDAuthor Information Associate Professor; Department of Nursing; University of Southern California; Los Angeles, California The Journal of Cardiovascular Nursing: July 2002 - Volume 16 - Issue 4 - p 9-20 Buy Abstract This article provides a comprehensive review of 30 years of research on the use of coenzyme Q10 in prevention and treatment of cardiovascular disease. This endogenous antioxidant has potential for use in prevention and treatment of cardiovascular disease, particularly hypertension, hyperlipidemia, coronary artery disease, and heart failure. It appears that levels of coenzyme Q10 are decreased during therapy with HMG-CoA reductase inhibitors, gemfibrozil, Adriamycin, and certain beta blockers. Further clinical trials are warranted, but because of its low toxicity it may be appropriate to recommend coenzyme Q10 to select patients as an adjunct to conventional treatment. Copyright © 2002 by Aspen Publishers, Inc.