This article discusses the current approach of using thrombolytic therapy as treatment for acute myocardial infarction (MI). The etiology of acute MI is reviewed along with recent research findings from definitive clinical trials. The mechanism of action of thrombolysis is described, and the available and investigational thrombolytic agents are compared. Complications of thrombolytic therapy and assessment indicators of reperfusion are presented. Key aspects of the nurse's role in the management of thrombolytic therapy are highlighted.
© 1989 Aspen Publishers, Inc.