CASE REPORT: PDF OnlyGallbladder Cancer Manifesting as Recurrent Common Bile Duct Stone and Duodenal Ulcer BleedingTsai, Tzung-Jiuna, d; Lai, Kwok-Hunga, d, *; Hsu, Ping-Ia, d; Tsai, Cheng-Chungb, d; Fu, Ting-Yingc, dAuthor Information aDivision of Gastroenterology, Kaohsiung Veterans General Hospital, Kaohsiung, Taipei, Taiwan, R.O.C. bDivision of General Surgery, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taipei, Taiwan, R.O.C. cDepartment of Pathology, Kaohsiung Veterans General Hospital, Kaohsiung, Taipei, Taiwan, R.O.C. dNational Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C. *Correspondence to: Dr Kwok-Hung Lai, Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, 386, Ta-Chung 1st Road, Kaohsiung 813, Taiwan, R.O.C. E-mail: [email protected] Received: December 2, 2008; • Accepted: June 10, 2009. Journal of the Chinese Medical Association: August 2009 - Volume 72 - Issue 8 - p 434-437 doi: 10.1016/S1726-4901(09)70401-0 Metrics Abstract Gallbladder cancer (GBC) is an uncommon disease and is usually asymptomatic. Poor prognosis and high mortality rate have been noted in patients with delayed diagnosis. We report a case of locally advanced GBC with duodenum and colon invasion manifesting as bleeding duodenal ulcer and recurrent common bile duct (CBD) stones. The patient was successfully treated with extended surgery. In patients who have multiple recurrence of CBD stones without common risk factors, concomitant biliary tract malignancy should be included in the differential diagnosis. © 2009 by Lippincott Williams & Wilkins, Inc.