Case Report: PDF OnlyMonostotic Vertebral Paget's Disease of the Lumbar SpineWu, Lien-Chen; Tseng, Chun-Hsiung; Chiang, Yueh-Feng; Tsuang, Yang-Hwei*Author Information aDepartment of Orthopedic Surgery, Taipei City Hospital, Taipei, Taiwan, R.O.C. *Correspondence to: Dr Yang-Hwei Tsuang, Department of Orthopedic Surgery, Taipei City Hospital, 145, Zheng Zhou Road, Taipei 103, Taiwan, R.O.C. E-mail: [email protected] Received: January 22, 2008; • Accepted: August 14, 2008. Journal of the Chinese Medical Association: January 2009 - Volume 72 - Issue 1 - p 52-55 doi: 10.1016/S1726-4901(09)70022-X Metrics Abstract Paget's disease in the Far East is quite rare. Age at diagnosis is usually greater than 50 years, and the disease typically affects the spine. Most patients are usually diagnosed with Paget's disease following radiographic examination for other purposes. It usually occurs at multiple vertebral levels, with only 10–25% of vertebral Paget's disease being monostotic. The disease rarely causes neurologic complications resulting from compression of intraspinal nerve tissue. Here, we present 2 cases of monostotic vertebral Paget's disease of the third lumbar vertebra. The first patient, who may be the first documented case of Paget's disease in the lumbar spine with progressive neurologic deficiency in an Asian population, received decompressive laminectomy due to marked spinal stenosis with neurologic deficits. The symptoms were greatly relieved following surgery, and ambulatory ability was restored. The second patient was diagnosed with Paget's disease following surgical biopsy. He remained asymptomatic at the most recent follow-up. © 2009 by Lippincott Williams & Wilkins, Inc.