Case Report: PDF OnlyLaryngotracheal Involvement as the Initial Manifestation of Relapsing PolychondritisChang, Shu-Jena; Lu, Chong-Chenb; Chung, Yu-Meic, e; Lee, Shinn-Shinga; Chou, Chung-Teid, e; Huang, De-Fengd, e, * Author Information aSection of Allergy, Immunology, and Rheumatology, Department of Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan, R.O.C. bSection of Clinical Pulmonary Physiology, Chest Department, Taipei, Taiwan, R.O.C. cDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C. dSection of Allergy, Immunology and Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C. eNational Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C. *Correspondence to: Dr. De-Feng Huang, Section of Allergy, Immunology and Rheumatology, Department of Medicine, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C. E-mail: [email protected] Received: June 30, 2004 • Accepted: November 25, 2004 Journal of the Chinese Medical Association: June 2005 - Volume 68 - Issue 6 - p 279-282 doi: 10.1016/S1726-4901(09)70151-0 Metrics Abstract Relapsing polychondritis (RP) is a rare multisystemic disease characterized by recurrent inflammation of cartilaginous and noncartilaginous tissues. When laryngotracheal or bronchial cartilages are involved, the disease can be life-threatening and needs aggressive treatment. Upper airway complaints are rare as initial presentations of RP. Here, however, we present a case of RP, with initial manifestations of cough and dyspnea that were treated as bronchial asthma for 6 months. Subglottic stenosis was found in April 2003, during a bronchoscopic examination, and emergency tracheostomy was performed. Auricular and nasal chondritis and bilateral scleritis developed 3 months after tracheostomy. High doses of methylprednisolone and immunosuppressive agents were used, and active inflammation in the eyes and ears was controlled, but the patient's upper airway was completely collapsed. This case is reported with the hope of increasing awareness about the potential for early upper airway involvement in RP. © 2005 by Lippincott Williams & Wilkins, Inc.