Case Report: PDF OnlyEpithelioid Hemangioendothelioma of the Nasal CavityTseng, Chih-Chieha; Tsay, Shyh-Hawb, c; Tsai, Tung-Lunga, *; Shu, Chih-Hunga, cAuthor Information aDepartment of Otolaryngology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C. bDepartment of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C. cNational Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C. *Correspondence to: Dr. Tung-Lung Tsai, Department of Otolaryngology, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C. E-mail: [email protected] Received: January 7, 2004 • Accepted: June 2, 2004 Journal of the Chinese Medical Association: January 2005 - Volume 68 - Issue 1 - p 45-48 doi: 10.1016/S1726-4901(09)70132-7 Metrics Abstract Epithelioid hemangioendothelioma (EH) is an unusual vascular neoplasm characterized by proliferation of endothelial cells with epithelioid morphology. It has an indolent course, with the potential for recurrence, but rarely metastasizes. The common locations include soft tissue, skin, viscera and bone. We present an unusual case of EH in the nasal cavity and describe the clinical characteristics, histopathologic findings, differential diagnosis and management. The 25-year-old male patient initially presented with an 8-month history of intermittent epistaxis. Nasal endoscopy revealed a vascular tumor involving the nasal cavity. The tumor was excised and the final histopathologic diagnosis was consistent with EH. EH in the head and neck is extremely rare. Wide excision is the treatment of choice, and regular follow-up is suggested due to the potential for recurrence. Definitive diagnosis depends on histopathologic and immunohistochemical features. © 2005 by Lippincott Williams & Wilkins, Inc.