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Squamous Cell Lung Cancer

Methotrexate Withdrawal Induced Spontaneous Regression of Liver Metastases

Hashimoto, Atsushi MD, PhD*; Kawasaki, Yuichiro MD*; Tominaga, Akito MD*; Kakutani, Takuya MD*; Kodama, Kako MD*; Nogi, Shinichi MD*; Tsuno, Hirotaka MD, PhD*; Ogihara, Hideki MD, PhD*; Nunokawa, Takahiro MD, PhD*; Ikenaka, Tatsuoh MD; Watai, Kentaro MD; Saito, Ikuo MD, PhD§; Matsui, Toshihiro MD, PhD*

doi: 10.1097/RHU.0000000000001010
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From the *Departments of Rheumatology, and


Clinical Research Center for Allergy and Rheumatology, and

§Department of Pathology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.

T.M. received research funding from Chugai Pharmaceutical Co, Ltd. The other authors declare no conflict of interest.

Correspondence: Atsushi Hashimoto, MD, PhD, Department of Rheumatology, National Hospital Organization Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku, Sagamihara, Kanagawa, 252-0392, Japan. E-mail:

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