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Illness Perception Mediates the Relationship Between the Severity of Symptoms and Perceived Health Status in Patients With Behçet Disease

Yankouskaya, Alla PhD*; Boughey, Alexandra MSc; McCagh, Jane PhD; Neal, Alison BSc(Hons); de Bezenac, Christophe PhD§; Davies, Simon J. PhD

JCR: Journal of Clinical Rheumatology: December 2019 - Volume 25 - Issue 8 - p 319–324
doi: 10.1097/RHU.0000000000000872
Original Articles

Objective The aim of this study was to investigate the relationship between psychological representations of illness, perceived health status, and self-assessment of symptom severity in patients with Behçet disease, a rare long-term incurable condition with unclear etiology.

Methods Using cross-sectional survey design, data on self-administered questionnaires on illness perception, health status, symptoms severity, and demographic characteristics were collected from 273 patients with Behçet disease (age range, 18–65 years). The data were subjected to mediation analysis to test whether cognitive and emotional components of illness perception mediate the relationship between the severity of symptoms and heath status.

Results The results support our hypotheses that cognitive components of illness perception (perceived consequences and identity of the illness) mediate the link between symptom activity and pain, whereas emotional components of the illness (emotional representations about the illness) mediate the relationship between disease activity and perceived energy level.

Conclusions The robustness of these mediation effects suggests potential directions for clinical psychologists and health care practitioners in developing support programs. We supplement our study with Open Access database containing information about type of medication, comorbid mood disorder, and detailed measurement of the severity of BD symptoms for sharing and accumulating multidisciplinary knowledge aiming to support the development of interventions. Addressing psychological aspects of BD will help to manage complex patients effectively.

From the *Department of Psychology, Bournemouth University, Poole

Department of Psychology, Liverpool Hope University, Liverpool

Allergy Therapeutics (UK) Ltd, Worthing

§University of Leeds, Leeds, England.

The authors declare no conflict of interest.

Correspondence: Alla Yankouskaya, PhD, Department of Psychology, Bournemouth University, Fern Barrow, Poole BH12 5BB, England. E-mail:

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Online date: July 26, 2018

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