Rheumatology RetrospectiveDid Michelangelo Have Gout?Pinals, Robert S. MD; Schlesinger, Naomi MDAuthor Information From the Division of Rheumatology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ. The authors declare no conflict of interest. Correspondence: Naomi Schlesinger, MD, Professor of Medicine Chief, Division of Rheumatology Department of Medicine Rutgers–Robert Wood Johnson Medical School MEB 468; PO Box 19, New Brunswick, NJ 08903–0019. E-mail: email@example.com. JCR: Journal of Clinical Rheumatology: October 2015 - Volume 21 - Issue 7 - p 364-367 doi: 10.1097/RHU.0000000000000301 Buy Metrics Abstract Michelangelo, the great Renaissance artist, is often included on lists of celebrated gout patients. His letters describe a single acute attack of foot pain at the age of 80, but a case for early onset has been presented, based on a fresco by a contemporary artist, Raphael. A figure resembling Michelangelo at the age of 36 appears to have nodules resembling tophi over his knees. In this report, we review Michelangelo's medical history, discuss the proposal that he had tophaceous gout, and address the significance of “knobby” knees in his works and those of other artists. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.