Patients with systemic lupus erythematosus (SLE) have a higher incidence rate of tuberculosis and a more frequent extrapulmonary involvement than the general population. We present 2 SLE patients who developed gastrointestinal tuberculosis complicated with intestinal perforation, a rare but serious complication that could be confused with lupus-associated intestinal vasculitis. Opportunistic infections such as tuberculosis must be suspected in SLE patients with abdominal symptoms on immunosuppressive therapy because its early recognition could prevent catastrophic complications such as intestinal perforation and subsequent peritonitis.
From the *Sección de Reumatología, Universidad de Antioquia, Hospital Universitario San Vicente Fundación; †Hospital Pablo Tobón Uribe; and ‡Sección de Inmunogenética, Universidad de Antioquia, Medellín, Colombia.
The authors declare no conflict of interest.
Correspondence: Luis A. Gonzàlez, MD, Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universidad de Antioquia, Calle 70 N° 52-21, zip code 229, Medellín, Antioquia, Colombia. E-mail: firstname.lastname@example.org.