Case ReportsFalse-Negative Dual-Energy Computed Tomography in a Patient With Acute GoutGlazebrook, Katrina N. MB, ChB*; Kakar, Sanjeev MD†; Ida, Cristiane M. MD‡; Laurini, Javier A. MD‡; Moder, Kevin G. MD§; Leng, Shuai PhD*Author Information From the Departments of *Radiology and †Orthopedic Surgery and Divisions of ‡Anatomic Pathology and §Rheumatology, Mayo Clinic, Rochester, MN. The authors declare no conflict of interest. Correspondence: Katrina N. Glazebrook, MB, ChB, Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905. E-mail: [email protected]. Journal of Clinical Rheumatology: April 2012 - Volume 18 - Issue 3 - p 138-141 doi: 10.1097/RHU.0b013e318253aa5e Buy Metrics AbstractIn Brief Gout is a painful inflammatory arthropathy caused by crystallization of monosodium urate within the joints. We present the case of a patient with primary gout who had positive results of joint aspiration and synovial biopsy for monosodium urate crystals in the third metacarpophalangeal joint but false-negative results of dual-energy computed tomography. Although DECT is very promising and likely to be specific for MSU deposition this case with microscopic crystal proof may have had too few crystals for detection. © 2012 Lippincott Williams & Wilkins, Inc.