Journal of Clinical Gastroenterology

Gastrointestinal Dysmotility in Critically Ill Patients
Biomarkers for Bile Acid Malabsorption in Diarrhea-predominant Irritable Bowel Syndrome
Adherence to Surveillance Endoscopies Posteradication of Barrett’s Esophagus With High-grade Dysplasia or Carcinoma In Situ
US Nationwide Insight Into All-cause 30-day Readmissions following Inpatient Endoscopic Retrograde Cholangiopancreatography

Current Issue

May/June 2023 - Volume 57 - Issue 5

Editor-in-Chief: Ronnie Fass, MD, FACG
ISSN: 0192-0790
Online ISSN: 1539-2031
Frequency: 10 issues / year
Ranking: Gastroenterology & Hepatology 70/93
Impact Factor: 3.174

Editor's Note

In their article, Diagnostic Accuracy of the Proton Pump Inhibitor Test in Gastroesophageal Reflux Disease and Noncardiac Chest Pain, Ghoneim et al., reassess the accuracy of the PPI test in GERD and noncardiac chest pain using systematic review and metanalysis. The results demonstrate that the PPI test is sensitive but with suboptimal specificity for detecting GERD in patients with typical symptoms. The PPI test demonstrated moderate-to-high accuracy in diagnosing GERD-related NCCP. While the PPI test performed slightly better in NERD, the overall diagnostic accuracy was comparable in both NERD and erosive esophagitis. This study further cement the value of the PPI test in GERD, specifically in patients presenting with typical symptoms and without alarm manifestation.

Ronnie Fass, MD