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Probiotics in 2015: Their Scope and Use

Sanders, Mary Ellen PhD

Journal of Clinical Gastroenterology: November/December 2015 - Volume 49 - Issue - p S2–S6
doi: 10.1097/MCG.0000000000000350

The field of probiotics continues to evolve and progress. This paper reviews several situations within the probiotic field that are of current interest, including review of the scope of the proper use of the term “probiotic,” use of systematic reviews and meta-analyses for probiotics, regulatory challenges to doing human research on probiotics in the United States, medical recommendations for probiotic use, and safety assurance for probiotics used for vulnerable populations. The greatest need in the probiotic field remains well-conducted and well-reported human trials, to better define the functionality of probiotics for different indications and populations.

Dairy & Food Culture Technologies, Centennial, CO

M.E.S. consults in the field of probiotics for several different probiotic food or dietary supplement companies but is not an owner or stockholder for any. She also serves on several scientific advisory boards. She serves as the Executive Science Officer for the International Scientific Association for Probiotics and Prebiotics.

Reprints: Mary Ellen Sanders, PhD, Dairy & Food Culture Technologies, 7119 S. Glencoe Ct., Centennial, CO 80122 (e-mail:

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