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A Survey of Potential Adherence to Capsule Colonoscopy in Patients Who Have Accepted or Declined Conventional Colonoscopy

Rex, Douglas K. MD; Lieberman, David A. MD

Journal of Clinical Gastroenterology: September 2012 - Volume 46 - Issue 8 - p 691–695
doi: 10.1097/MCG.0b013e31824432df
ALIMENTARY TRACT: Original Articles

Background: Capsule colonoscopy might improve adherence to colorectal cancer screening.

Objective: Measure attractiveness of capsule colonoscopy in patients who have declined conventional colonoscopy, using patients who have undergone colonoscopy as a control group.

Design: Internet-based survey.

Setting: United States.

Subjects: A total of 308 geographically diverse, high school or higher educated, middle to upper income, insured internet users who had been offered colonoscopy previously.

Interventions: Survey.

Main Outcome Measurements: Preferences for colonoscopy, capsule colonoscopy, fecal occult blood test, or no screening.

Results: After a description of capsule technology features relative to colonoscopy, including “no need for a ride,” “no time off work,” “approximately 5% less accurate,” “booster preparation needed,” and “follow-up colonoscopy needed in 20% of patients,” preference for capsule colonoscopy was shown by 24% of those who had undergone colonoscopy and 49% of those who had not. “No need for a ride” and “no time off work” were considered positive features of capsule colonoscopy. The potential to undergo capsule colonoscopy during the weekend was also considered attractive.

Limitations: Restricted population.

Conclusions: The availability of capsule colonoscopy could potentially increase colorectal cancer screening adherence rates among patients who decline screening colonoscopy.

Supplemental Digital Content is available in the text.

Indiana University Hospital, University Boulevard, Indianapolis, IN

Supplemental Digital Content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website,

Given Imaging Corp. paid ZS Associates for development of the survey and Toluna Corporation to conduct the survey. Dr Rex has received research support from Given Imaging.

Drs Rex and Lieberman are paid consultants to Given Imaging.

Reprints: Douglas K. Rex, MD, Indiana University Hospital #4100, 550 N. University Boulevard, Indianapolis, IN 46202 (e-mail:

Received July 15, 2011

Accepted November 29, 2011

© 2012 Lippincott Williams & Wilkins, Inc.