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A Comprehensive Review of Eosinophilic Esophagitis in Adults

Almansa, Cristina MD; DeVault, Kenneth R. MD; Achem, Sami R. MD

Journal of Clinical Gastroenterology: September 2011 - Volume 45 - Issue 8 - p 658–664
doi: 10.1097/MCG.0b013e318211f95b

Eosinophilic esophagitis is a recently described disease characterized by the presence of upper gastrointestinal tract symptoms in association with a dense esophageal eosinophilic infiltrate. The awareness and interest of physicians and researchers in this disease has been increasing as reflected by the number of publications on this topic in the last 5 years. The aim of this review is to summarize the latest evidence with regard to epidemiology, pathogenesis, diagnostic, and management of eosinophilic esophagitis, primarily in adults and selected areas in children.

Gastroenterology Division, Mayo Clinic Florida, Jacksonville, FL

Funding Source: Dr Almansa is supported by an educational grant from Boston Scientific.

The authors have nothing to disclose relevant to this manuscript.

Reprints: Sami R. Achem, MD, Mayo College of Medicine, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224 (e-mail:

© 2011 Lippincott Williams & Wilkins, Inc.