The Role of Probiotics in the Clinical Management of Food Allergy and Atopic DermatitisMiraglia del Giudice, M; De Luca, M GJournal of Clinical Gastroenterology: July 2004 - Volume 38 - Issue - p S84-S85 doi: 10.1097/01.mcg.0000133293.18576.d2 Probiotics, Prebiotics, and New Foods Abstract Author Information The probiotics are cultures of potentially benefitial bacteria that positively affects host by enhancing the microbial balance and therefore restore the normal intestinal permeability and gut microecology, improve the intestine’s immunologic barrier function and reduce the generation of proinflammatory cycochines characteristics of allergic inflammation. The authors made a survey of the most relevant studies concerning the use of probiotics in the food allergy, atopic dermatitis, and in primary prevention of atopy. On the basis of these trials probiotic therapy alleviates allergic inflammation as demonstrated by the control of clinical symptoms and the reduction of local and systemic inflammatory markers. Received for publication January 13, 2004; accepted February 18, 2004. From the Dipartimento di Pediatria, Seconda Università di Napoli, Italy. Reprints: Michelle Miraglia del Giudice, Seconda Università di Napoli, Via Sant’ Andrea Delle Dame 4, 80100 Naples, Italy (e-mail: firstname.lastname@example.org). © 2004 Lippincott Williams & Wilkins, Inc.