Probiotics, Prebiotics, and New FoodsProbiotics and Functional Abdominal BloatingDi Stefano, M MD; Miceli, E MD; Armellini, E MD; Missanelli, A MD; Corazza, G R MD Author Information From the Gastroenterology Unit, IRCCS “S. Matteo” Hospital, University of Pavia, Italy. Received for publication January 14, 2004; accepted February 12, 2004. Reprints: Prof. G. R. Corazza, Gastroenterology Unit, IRCCS “S. Matteo” Hospital, University of Pavia, Viale Golgi 19, 27100 Pavia, Italy (e-mail: [email protected]). Journal of Clinical Gastroenterology 38():p S102-S103, July 2004. | DOI: 10.1097/01.mcg.0000128939.40458.25 Buy Metrics Abstract Functional abdominal bloating is a condition dominated by a feeling of abdominal fullness or bloating and without sufficient criteria for another functional gastrointestinal disorder. The currently used therapeutic approaches aim to reduce the volume of intestinal gas, thus increasing intestinal gas elimination or reducing its production. Some promising results have been obtained by the use of prokinetics, such as tegaserod and Prostigmine, and by the use of nonabsorbable antibiotics, such as rifaximin. Another therapeutic approach is represented by the administration of probiotics to modify the composition of colonic flora and thus the production of intestinal gas. The authors recently studied the effect of LGG, which proved to be more effective than placebo in reducing the severity of symptoms. © 2004 Lippincott Williams & Wilkins, Inc.