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Diaphragm Disease of the Small Bowel: A Case Without Apparent Nonsteroidal Antiinflammatory Drug Use

Santolaria, Santos M.D.; Cabezali, Roger M.D.; Ortego, Javier M.D.; Castiella, Tomas M.D.; Salinas, Jose C. M.D.; Lanas, Angel M.D.

Journal of Clinical Gastroenterology: April 2001 - Volume 32 - Issue 4 - p 344-346
Case Reports

Background Diaphragm-like strictures of the small bowel are an infrequent complication of the treatment of patients with nonsteroidal antiinflammatory drugs (NSAIDs).

Study We report a patient with this condition in whom the use of NSAIDs was ruled out by both clinical history and objective blood testing of current aspirin use.

Results He reported a history of recurrent episodes of colic abdominal pain during the past 25 years; he underwent three surgical operations for this condition. Before these symptoms, he had an undefined abdominal process with diarrhea, weight loss, and diffuse edema, which resolved spontaneously without reaching a diagnosis.

Conclusions We suggest that diaphragm-like strictures might be developed as a nonspecific response to different damaging insults to the intestine and are not necessarily associated with NSAID use.

From the Service of Gastroenterology (S.S., A.L.), the Department of Surgery (R.C., J.C.S.), and the Department of Pathology (J.O., T.C.), University Hospital “Lozano Blesa,” Zaragoza, Spain.

Submitted July 20, 1999.

Accepted October 8, 1999.

Address correspondence and reprint requests to Dr. Angel Lanas, Service of Gastroenterology, University Hospital, 50009 Zaragoza, Spain. E-mail:

© 2001 Lippincott Williams & Wilkins, Inc.