Nonomura Akitaka M.D.; Mizukami, Yuji M.D.; Kadoya, Masumi M.D.; Takayanagi, Nobutatsu M.D.; Hirono, Teisuke M.D.Journal of Clinical Gastroenterology: April 1995 Case Studies: PDF Only Buy Abstract Angiomyolipoma (AML) of the liver is extremely rare; we believe only about 60 cases, all solitary, have been reported. We present here the first reported case, to our knowledge, of multiple AMLs in the liver. Two masses were found in the liver of a 43-year-old Japanese woman complaining of abdominal discomfort by ultrasonography and computed tomography. With a preoperative diagnosis of hepatocellular carcinoma, a tumor in the right lobe 4.0 cm in largest diameter and one in the left lobe measuring 2.4 cm were resected. Histologically, both tumors were composed of smooth-muscle cells, fat cells, and blood vessels, and contained foci of extramedullary hematopoiesis. Although the smooth-muscle cell component was predominant and both tumors exhibited some pleomorphism, no mitosis was found. These histologic findings are consistent with the diagnosis of AML. © Lippincott-Raven Publishers.