Editorials: PDF OnlySubramanyam Kalyanam M.D.; Rajan, Rajeshwari T. M.D.; Hearn, C. David M.D.Journal of Clinical Gastroenterology: February 1988 - p 98-100 Free Abstract Barium granuloma (BG) is an unusual complication of barium enema that occurs due to the intravasation of barium into the colonie wall as a result of mucosal injury from an enema tip, overinflation of the rectal balloon, or intrinsic disease such as ulcerative colitis. We report a case of BG from a barium enema performed within 24 h after a proctoscopic biopsy. It was detected 5 years later when the patient developed persistent low back pain. © Lippincott-Raven Publishers.