Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Computational Modeling of Gold Nanoparticle in Lung Cancer Photothermal Therapy

Yahya, Ibtihag; Eltayeb, Megdi PhD

doi: 10.1097/JCE.0000000000000354
FEATURE ARTICLES
Buy

Today, the biological compatibility properties of gold nanoparticles (AuNPs) have made them an important area for research in medical applications such as cancer diagnosis, treatment, and imaging. This article seeks to address the potential of precious metals such as AuNPs in the treatment of cancerous cells using COMSOL Multiphysics to model heat transfer in lung carcinoid tumor. The study also investigated and discussed how to harness the gold power and properties in killing cancer cells without harming the healthy ones. One of the more significant findings to emerge from this study is that both PDE (diffusion equation) and heat transfer modules can model the thermal activation of the AuNP and predict the thermal profile inside the tumor successfully.

Corresponding author: Megdi Eltayeb, PhD, Department of Biomedical Engineering of Sudan University of Science and Technology, PO Box 407, Khartoum, Sudan, and can be reached at megdi.eltayeb@gmail.com or megdi.eltayeb@sustech.edu.

Ibtihag Yahya is a researcher in the Department of Biomedical Engineering of Sudan University of Science and Technology, Khartoum.

Megdi Eltayeb, PhD, is assistant professor in biomedical engineering at the Sudan University of Science and Technology in Khartoum, Sudan.

The authors declare no conflicts of interest.

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.